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Titel:

Genetic analysis of MAPT haplotype diversity in frontotemporal dementia.

Dokumenttyp:
Journal Article; Article
Autor(en):
Laws, SM; Friedrich, P; Diehl-Schmid, J; Muller, J; Ibach, B; Bäuml, J; Eisele, T; Förstl, H; Kurz, A; Riemenschneider, M
Abstract:
The H1 haplotype of the tau gene, MAPT, has been linked to the sporadic tauopathies corticobasal degeneration and progressive supranuclear palsy; however, there have been inconsistent findings regarding association with frontotemporal dementia (FTD). We investigated MAPT haplotype diversity, in 171 sporadic FTD and 186 healthy controls individuals, and report no single marker or haplotype association with increased risk or changes in age at onset. These findings do not support an association of...     »
Zeitschriftentitel:
Neurobiol Aging
Jahr:
2008
Band / Volume:
29
Heft / Issue:
8
Seitenangaben Beitrag:
1276-8
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.neurobiolaging.2007.02.019
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17386961
Print-ISSN:
0197-4580
TUM Einrichtung:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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