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Title:

Testing of antidotes for organophosphorus compounds: Experimental procedures and clinical reality.

Document type:
Journal Article
Author(s):
Eyer, P; Szinicz, L; Thiermann, H; Worek, F; Zilker, T
Abstract:
According to current knowledge, inhibition of acetylcholinesterase (AChE) is a very important toxic action of organphosphorus compounds (OP). Hence, it is obvious to follow the AChE activity in order to quantify the degree of inhibition and to assess possible reactivation. Red blood cell (RBC)-AChE provides an easily accessible source to follow the AChE status also in humans. There are many reports underlining the appropriateness of RBC-AChE as a surrogate parameter that mirrors the synaptic enz...     »
Journal title abbreviation:
Toxicology
Year:
2007
Journal volume:
233
Journal issue:
1-3
Pages contribution:
108-19
Language:
eng
Fulltext / DOI:
doi:10.1016/j.tox.2006.08.033
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17010492
Print-ISSN:
0300-483X
TUM Institution:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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