User: Guest  Login
Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Timmermann, L; Braun, M; Groiss, S; Wojtecki, L; Ostrowski, S; Krause, H; Pollok, B; Südmeyer, M; Ploner, M; Gross, J; Maarouf, M; Voges, J; Sturm, V; Schnitzler, A
Title:
Differential effects of levodopa and subthalamic nucleus deep brain stimulation on bradykinesia in Parkinson's disease.
Abstract:
Cardinal symptoms of Parkinson's disease (PD) respond well to treatment with levodopa and deep brain stimulation (DBS) of the subthalamic nucleus (STN). However, it has remained unclear whether levodopa and STN-DBS have differential effects on bradykinesia. We investigated 8 PD-patients with STN-electrodes in four conditions: STN-DBS and levodopa (ON(MED)/ON(STIM)), STN-DBS only (OFF(MED)/ON(STIM)), levodopa only (ON(MED)/OFF(STIM)), without STN-DBS/levodopa (OFF(MED)/OFF(STIM)). Fourteen volunt...    »
Journal title abbreviation:
Mov Disord
Year:
2008
Journal volume:
23
Journal issue:
2
Pages contribution:
218-27
Language:
eng
Fulltext / DOI:
doi:10.1002/mds.21808
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18044706
Print-ISSN:
0885-3185
TUM Institution:
Neurologische Klinik und Poliklinik
 BibTeX