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Document type:
Journal Article; Article 
Author(s):
Muhlau, M; Gaser, C; Wohlschläger, AM; Weindl, A; Städtler, M; Valet, M; Zimmer, C; Kassubek, J; Peinemann, A 
Title:
Striatal gray matter loss in Huntington's disease is leftward biased. 
Abstract:
In Huntington's disease (HD), the distribution of pathological changes throughout the brain is incompletely understood. Some studies have identified leftward-biased lateralization, whereas others did not. We performed magnetic resonance imaging and a voxel-based asymmetry analysis in 44 right-handed HD gene carriers (presymptomatic, n = 5; stage I, n = 28; stage II, n = 11) and 44 right-handed healthy controls. The group comparison revealed leftward-biased gray matter loss in the striatum. Fur...    »
 
Journal title abbreviation:
Mov Disord 
Year:
2007 
Journal volume:
22 
Journal issue:
Pages contribution:
1169-73 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0885-3185 
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Neurologische Klinik und Poliklinik