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Title:

Levels of three distinct p75 neurotrophin receptor forms found in human plasma are altered in type 2 diabetic patients.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Humpert, PM; Kopf, S; Djuric, Z; Laine, K; Korosoglou, G; Rudofsky, G; Hamann, A; Morcos, M; von Eynatten, M; Nawroth, PP; Bierhaus, A
Abstract:
AIMS/HYPOTHESIS: The p75 neurotrophin receptor (p75NTR) has been shown to appear in the plasma of diabetic rats, possibly indicating diabetic neuropathy. The aim of this study was to use a semi-quantitative assay for human plasma p75NTR to investigate whether this receptor is a marker of peripheral diabetic neuropathy (DPN) and autonomic cardiovascular neuropathy (CAN) in type 2 diabetic patients. SUBJECTS AND METHODS: Eighty type 2 diabetic patients and 25 controls without diabetes were analyse...     »
Journal title abbreviation:
Diabetologia
Year:
2007
Journal volume:
50
Journal issue:
7
Pages contribution:
1517-22
Language:
eng
Fulltext / DOI:
doi:10.1007/s00125-007-0683-3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17492429
Print-ISSN:
0012-186X
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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