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Document type:
Journal Article
Author(s):
Gamboa-Dominguez, A; Seidl, S; Reyes-Gutierrez, E; Hermannstädter, C; Quintanilla-Martinez, L; Busch, R; Höfler, H; Fend, F; Luber, B
Title:
Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer.
Abstract:
BACKGROUND: Gastric carcinoma is characterised by numerous genetic and epigenetic alterations that influence cell cycle progression, apoptosis and DNA repair. These alterations include down-regulation of the cyclin-dependent kinase (CDK) inhibitors p21(WAF1/CIP1) and p27(Kip1), and mutations of the tumour suppressor protein p53 and the cell adhesion molecule E-cadherin. Combined evaluation of the prognostic significance of these alterations has not been reported in Mexican Mestizo patients. AIMS...    »
Journal title abbreviation:
J Clin Pathol
Year:
2007
Journal volume:
60
Journal issue:
7
Pages contribution:
756-61
Language:
eng
Fulltext / DOI:
doi:10.1136/jcp.2006.038976
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17483253
Print-ISSN:
0021-9746
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie
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