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Titel:

Improvement of safety profile of docetaxel by weekly administration in patients with metastatic breast cancer.

Dokumenttyp:
Journal Article; Article
Autor(en):
Warm, M; Nawroth, F; Ohlinger, R; Valter, M; Pantke, E; Mallmann, P; Harbeck, N; Kates, R; Thomas, A
Abstract:
BACKGROUND: This is a retrospective cohort study on the safety and efficacy profiles of weekly docetaxel at varying doses in patients with pretreated metastatic breast cancer. PATIENTS AND METHODS: Twenty-five anthracycline-pretreated patients received docetaxel administered on a weekly basis, as a one-hour infusion, at various dosage levels (25, 30, 35, 40 mg/m2) depending on their baseline Karnofsky index. Each 8-week cycle consisted of 6 weeks of drug infusion, followed by a 2-week rest perio...     »
Zeitschriftentitel:
Onkologie
Jahr:
2007
Band / Volume:
30
Heft / Issue:
8-9
Seitenangaben Beitrag:
436-41
Sprache:
eng
Volltext / DOI:
doi:10.1159/0000104415
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17848815
Print-ISSN:
0378-584X
TUM Einrichtung:
Frauenklinik und Poliklinik
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