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Document type:
Journal Article
Author(s):
Kruger, A; Krebs, T; Banke, IJ
Title:
Anti-metastatic effects of serine protease inhibitors: animal models for analysis.
Abstract:
To date, no effective adjuvant drug preventing the aggressive spread of tumour cells in late stages of cancer disease or at the time-point of primary tumour removal is available. Although proteases, including members of the large serine protease family, were shown to be promising targets for an anti-metastatic cancer therapy, synthetic protease inhibitors (SPIs) have so far failed to be introduced into the clinic. In addition to considerations in the design of classical in vivo -tests of SPIs as...    »
Journal title abbreviation:
Hamostaseologie
Year:
2007
Journal volume:
27
Journal issue:
1
Pages contribution:
64-70
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17279279
Print-ISSN:
0720-9355
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
Format:
Text
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