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Title:

Putative association of a TLR9 promoter polymorphism with atopic eczema.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Novak, N; Yu, CF; Bussmann, C; Maintz, L; Peng, WM; Hart, J; Hagemann, T; Díaz-Lacava, A; Baurecht, HJ; Klopp, N; Wagenpfeil, S; Behrendt, H; Bieber, T; Ring, J; Illig, T; Weidinger, S
Abstract:
BACKGROUND: Toll-like receptors (TLR) play a pivotal role in the induction of first-line defense mechanisms of the innate immune system and trigger adaptive immune responses to microbial pathogens. Genetic variations in innate immunity genes have been reported to be associated with a range of inflammatory disorders. Deficiencies on the level of immunity receptors such as pathogen-recognition receptors are suspected to affect the maturation of our immune system and to avail thereby the high preva...     »
Journal title abbreviation:
Allergy
Year:
2007
Journal volume:
62
Journal issue:
7
Pages contribution:
766-72
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1398-9995.2007.01358.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17573724
Print-ISSN:
0105-4538
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Dermatologie und Allergologie
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