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Titel:

The influence of HIV infection and antiretroviral therapy on the mitochondrial membrane potential of peripheral mononuclear cells.

Dokumenttyp:
Clinical Trial; Comparative Study; Journal Article
Autor(en):
Sternfeld, T; Schmid, M; Tischleder, A; Mudra, S; Schlamp, A; Kost, BP; Gruber, R; Youle, M; Bogner, JR; Goebel, FD
Abstract:
OBJECTIVES: Clinical disorders occurring in HIV-infected patients on antiretroviral therapy (ART) have been linked to mitochondrial dysfunction, for example, lactic acidosis and lipodystrophy. Mitochondrial membrane potential (delta psi m) is the most direct measure of the state of energization of the mitochondria. We analysed delta psi m, of peripheral blood mononuclear cells (PBMCs) in HIV-negative, healthy subjects (n=8), HIV-infected, treatment-naive patients (n=30), and HIV-infected patient...     »
Zeitschriftentitel:
Antivir Ther
Jahr:
2007
Band / Volume:
12
Heft / Issue:
5
Seitenangaben Beitrag:
769-78
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17713160
Print-ISSN:
1359-6535
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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