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Title:

Identification of causal effects of neuroanatomy on cognitive decline requires modeling unobserved confounders.

Document type:
Journal Article
Author(s):
Pölsterl, Sebastian; Wachinger, Christian
Abstract:
INTRODUCTION: Carrying out a randomized controlled trial to estimate the causal effects of regional brain atrophy due to Alzheimer's disease (AD) is impossible. Instead, we must estimate causal effects from observational data. However, this generally requires knowing and having recorded all confounders, which is often unrealistic. METHODS: We provide an approach that leverages the dependencies among multiple neuroanatomical measures to estimate causal effects from observational neuroimaging data...     »
Journal title abbreviation:
Alzheimers Dement
Year:
2023
Journal volume:
19
Journal issue:
5
Pages contribution:
1994-2005
Fulltext / DOI:
doi:10.1002/alz.12825
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36419215
Print-ISSN:
1552-5260
TUM Institution:
Institut für Diagnostische und Interventionelle Radiologie
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