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Titel:

Independent Tissue-Based Biomarkers in Endometrioid Endometrial Cancer: Tumor Budding in Microsatellite Instability and WHO Grading in Copy-Number-Low Patients.

Dokumenttyp:
Article; Journal Article
Autor(en):
Stögbauer, Fabian; Geß, Barbara; Brambs, Christine; Lautizi, Manuela; Kacprowski, Tim; Ourailidis, Iordanis; Bronger, Holger; Kiechle, Marion; Noske, Aurelia; Keller, Gisela; Jesinghaus, Moritz; Poremba, Christopher; Weichert, Wilko; Boxberg, Melanie
Abstract:
The molecular characterization of endometrial endometrioid adenocarcinomas has provided major advances in its prognostic stratification. However, risk assessment of microsatellite instability (MSI) and copy-number (CN)-low cases remains a challenge. Thus, we aimed to identify tissue-based morphologic biomarkers that might help in the prognostic stratification of these cases. Histomorphologic parameters (WHO grading, tumor budding (TB), tumor-stroma ratio (as a quantitative description of stromal...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2023
Band / Volume:
15
Heft / Issue:
15
Volltext / DOI:
doi:10.3390/cancers15153832
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37568650
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Klinik und Poliklinik für Frauenheilkunde (Prof. Kiechle)
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