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Title:

An energy costly architecture of neuromodulators for human brain evolution and cognition.

Document type:
Journal Article
Author(s):
Castrillon, Gabriel; Epp, Samira; Bose, Antonia; Fraticelli, Laura; Hechler, André; Belenya, Roman; Ranft, Andreas; Yakushev, Igor; Utz, Lukas; Sundar, Lalith; Rauschecker, Josef P; Preibisch, Christine; Kurcyus, Katarzyna; Riedl, Valentin
Abstract:
In comparison to other species, the human brain exhibits one of the highest energy demands relative to body metabolism. It remains unclear whether this heightened energy demand uniformly supports an enlarged brain or if specific signaling mechanisms necessitate greater energy. We hypothesized that the regional distribution of energy demands will reveal signaling strategies that have contributed to human cognitive development. We measured the energy distribution within the brain functional connec...     »
Journal title abbreviation:
Sci Adv
Year:
2023
Journal volume:
9
Journal issue:
50
Fulltext / DOI:
doi:10.1126/sciadv.adi7632
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38091393
Print-ISSN:
2375-2548
TUM Institution:
Klinik für Anästhesiologie (DHM); Klinik und Poliklinik für Nuklearmedizin (Prof. Weber); Professur für Neuroradiologie (Prof. Zimmer)
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