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Title:

Metabolic reprogramming: Unveiling the therapeutic potential of targeted therapies against kidney disease.

Document type:
Journal Article; Review
Author(s):
Saxena, Shubhangi; Dagar, Neha; Shelke, Vishwadeep; Lech, Maciej; Khare, Pragyanshu; Gaikwad, Anil Bhanudas
Abstract:
As a high-metabolic-rate organ, the kidney exhibits metabolic reprogramming (MR) in various disease states. Given the >800 million cases of kidney disease worldwide in 2022, understanding the specific bioenergetic pathways involved and developing targeted interventions are vital needs. The reprogramming of metabolic pathways (glucose metabolism, amino acid metabolism, etc.) has been observed in kidney disease. Therapies targeting these specific pathways have proven to be an efficient approach fo...     »
Journal title abbreviation:
Drug Discov Today
Year:
2023
Journal volume:
28
Journal issue:
11
Fulltext / DOI:
doi:10.1016/j.drudis.2023.103765
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37690600
Print-ISSN:
1359-6446
TUM Institution:
Professur für Nephrologie (Prof. Heemann)
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