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Titel:

Lupus Nephritis: New and Emerging Biologic and Targeted Therapies.

Dokumenttyp:
Review; Journal Article; Review
Autor(en):
Kale, Ajinath; Lech, Maciej; Anders, Hans-Joachim; Gaikwad, Anil Bhanudas
Abstract:
Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), a polyclonal systemic autoimmunity directed against nuclear and other self-antigens. SLE/LN affects mostly females during childbearing age, which puts them at risk for the progression of chronic kidney disease (CKD), cardiovascular disease, and pregnancy complications. The current management of LN involves the use of drugs with significant toxicities, and despite many attempts at novel drug interventions, the ov...     »
Zeitschriftentitel:
BioDrugs
Jahr:
2023
Band / Volume:
37
Heft / Issue:
4
Seitenangaben Beitrag:
463-475
Volltext / DOI:
doi:10.1007/s40259-023-00597-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37093522
Print-ISSN:
1173-8804
TUM Einrichtung:
602; Professur für Nephrologie (Prof. Heemann)
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