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Title:

Efficacy, Retention and Tolerability of Everolimus in Patients with Tuberous Sclerosis Complex: A Survey-Based Study on Patients' Perspectives.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Willems, Laurent M; Rosenow, Felix; Schubert-Bast, Susanne; Kurlemann, Gerhard; Zöllner, Johann Philipp; Bast, Thomas; Bertsche, Astrid; Bettendorf, Ulrich; Ebrahimi-Fakhari, Daniel; Grau, Janina; Hahn, Andreas; Hartmann, Hans; Hertzberg, Christoph; Hornemann, Frauke; Immisch, Ilka; Jacobs, Julia; Klein, Karl Martin; Klotz, Kerstin A; Kluger, Gerhard; Knake, Susanne; Knuf, Markus; Marquard, Klaus; Mayer, Thomas; Meyer, Sascha; Muhle, Hiltrud; Müller-Schlüter, Karen; von Podewils, Felix; Ruf, Sus...     »
Abstract:
BACKGROUND: The approval of everolimus (EVE) for the treatment of angiomyolipoma (2013), subependymal giant cell astrocytoma (2013) and drug-refractory epilepsy (2017) in patients with tuberous sclerosis complex (TSC) represents the first disease-modifying treatment option available for this rare and complex genetic disorder. OBJECTIVE: The objective of this study was to analyse the use, efficacy, tolerability and treatment retention of EVE in patients with TSC in Germany from the patient's pers...     »
Journal title abbreviation:
CNS Drugs
Year:
2021
Journal volume:
35
Journal issue:
10
Pages contribution:
1107-1122
Fulltext / DOI:
doi:10.1007/s40263-021-00839-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34275102
Print-ISSN:
1172-7047
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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