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Title:

Nephrotic-range proteinuria in type 2 diabetes: Effects of empagliflozin on kidney disease progression and clinical outcomes.

Document type:
Journal Article
Author(s):
Ruggenenti, Piero; Kraus, Bettina J; Inzucchi, Silvio E; Zinman, Bernard; Hantel, Stefan; Mattheus, Michaela; von Eynatten, Maximilian; Remuzzi, Giuseppe; Koitka-Weber, Audrey; Wanner, Christoph
Abstract:
Background: Diabetic kidney disease with nephrotic-range proteinuria (NRP) is commonly associated with rapid kidney function loss, increased cardiovascular risk, and premature mortality. We explored the effect of empagliflozin in patients with type 2 diabetes and cardiovascular disease, complicated by presence of this major risk factor for progressive kidney disease, in a post-hoc analysis of data from the EMPA-REG OUTCOME trial (NCT01131676). Methods: Cox proportional hazards models were used t...     »
Journal title abbreviation:
EClinicalMedicine
Year:
2022
Journal volume:
43
Fulltext / DOI:
doi:10.1016/j.eclinm.2021.101240
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35005582
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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