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Title:

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions.

Document type:
Journal Article; Meeting Abstract
Author(s):
Eken, Suzanne M; Jin, Hong; Chernogubova, Ekaterina; Li, Yuhuang; Simon, Nancy; Sun, Changyan; Korzunowicz, Greg; Busch, Albert; Bäcklund, Alexandra; Österholm, Cecilia; Razuvaev, Anton; Renné, Thomas; Eckstein, Hans Henning; Pelisek, Jaroslav; Eriksson, Per; González Díez, María; Perisic Matic, Ljubica; Schellinger, Isabel N; Raaz, Uwe; Leeper, Nicholas J; Hansson, Göran K; Paulsson-Berne, Gabrielle; Hedin, Ulf; Maegdefessel, Lars
Abstract:
In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets.To investigate miRNAs of clinical interest in patients with unstable carotid stenosis at risk of stroke.Using patient material from the BiKE (Biobank of Karolinska Endarterectomies), we profiled miRNA expression in patients with stable versus unstable carotid plaque. A polymerase chain reaction-based miRNA array of plasma, sampled at the carotid lesion site, identified 8 de...     »
Journal title abbreviation:
Circ Res
Year:
2017
Journal volume:
120
Journal issue:
4
Pages contribution:
633-644
Language:
eng
Fulltext / DOI:
doi:10.1161/CIRCRESAHA.116.309318
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27895035
Print-ISSN:
0009-7330
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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