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Titel:

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions.

Dokumenttyp:
Journal Article; Meeting Abstract
Autor(en):
Eken, Suzanne M; Jin, Hong; Chernogubova, Ekaterina; Li, Yuhuang; Simon, Nancy; Sun, Changyan; Korzunowicz, Greg; Busch, Albert; Bäcklund, Alexandra; Österholm, Cecilia; Razuvaev, Anton; Renné, Thomas; Eckstein, Hans Henning; Pelisek, Jaroslav; Eriksson, Per; González Díez, María; Perisic Matic, Ljubica; Schellinger, Isabel N; Raaz, Uwe; Leeper, Nicholas J; Hansson, Göran K; Paulsson-Berne, Gabrielle; Hedin, Ulf; Maegdefessel, Lars
Abstract:
In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets.To investigate miRNAs of clinical interest in patients with unstable carotid stenosis at risk of stroke.Using patient material from the BiKE (Biobank of Karolinska Endarterectomies), we profiled miRNA expression in patients with stable versus unstable carotid plaque. A polymerase chain reaction-based miRNA array of plasma, sampled at the carotid lesion site, identified 8 de...     »
Zeitschriftentitel:
Circ Res
Jahr:
2017
Band / Volume:
120
Heft / Issue:
4
Seitenangaben Beitrag:
633-644
Sprache:
eng
Volltext / DOI:
doi:10.1161/CIRCRESAHA.116.309318
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27895035
Print-ISSN:
0009-7330
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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