Impact of the operative technique on mid- and long-term results following paediatric heart transplantation.

Rosenthal, L Lily; Grinninger, Carola; Pozza, Robert Dalla; Fischer, Marcus; Zimmerling, Linda; Ulrich, Sarah M; Kari, Fabian A; Haas, Nikolaus A; Michel, Sebastian; Hörer, Jürgen; Hagl, Christian

doi:10.1002/ehf2.14718

Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum

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Title:: Impact of the operative technique on mid- and long-term results following paediatric heart transplantation.
Document type:: Journal Article
Author(s):: Rosenthal, L Lily; Grinninger, Carola; Pozza, Robert Dalla; Fischer, Marcus; Zimmerling, Linda; Ulrich, Sarah M; Kari, Fabian A; Haas, Nikolaus A; Michel, Sebastian; Hörer, Jürgen; Hagl, Christian
Abstract:: AIMS: The aim of this study is to evaluate and compare the impact of the bicaval technique versus the biatrial technique (by Lower and Shumway) in paediatric heart transplant patients. Only a few studies investigate this matter regarding the long-term outcome after paediatric heart transplantation. We compared the two surgical methods regarding survival, the necessity of pacemaker implantation. METHODS AND RESULTS: All 134 patients (aged <18 years) - (group-1) biatrial (n = 84), versus (group-2) bicaval (n = 50), who underwent heart transplantation between October 1988 and December 2021, were analysed. Freedom from events were estimated using the Kaplan-Meier method. Potential differences were analysed using the log rank test and Cox proportional hazard models. Mean ± standard deviation: Bypass time (per minutes) was higher in the group 1 as compared with group 2 (P = 0.050). Survival was not significantly different (P = 0.604) in either groups. Eighteen patients required permanent pacemaker implantation in the group 1 and only one patient required it in the group 2 (P = 0.001). CONCLUSIONS: Paediatric heart transplantation using bicaval technique results similar long-term survival compared with the biatrial technique. The incidence of atrial rhythm disorders was significantly higher in the biatrial group, requiring a higher frequency of pacemaker implantation in this group. As a results, the bicaval technique has replaced the biatrial technique in our centre.
Journal title abbreviation:: ESC Heart Fail
Year:: 2024
Journal volume:: 11
Journal issue:: 3
Pages contribution:: 1602-1611
Fulltext / DOI:: doi:10.1002/ehf2.14718
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/38378979
Print-ISSN:: 2055-5822
TUM Institution:: 612; Klinik für Chirurgie angeborener Herzfehler und Kinderherzchirurgie (DHM) (Prof. Hörer)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Chirurgie angeborener Herzfehler und Kinderherzchirurgie (DHM) (Prof. Hörer)2024