Benutzer: Gast  Login
Titel:

Establishment of a 3D Model to Characterize the Radioresponse of Patient-Derived Glioblastoma Cells.

Dokumenttyp:
Journal Article
Autor(en):
Strand, Zoe; Schrickel, Finn; Dobiasch, Sophie; Thomsen, Andreas R; Steiger, Katja; Gempt, Jens; Meyer, Bernhard; Combs, Stephanie E; Schilling, Daniela
Abstract:
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Despite modern, multimodal therapeutic options of surgery, chemotherapy, tumor-treating fields (TTF), and radiotherapy, the 5-year survival is below 10%. In order to develop new therapies, better preclinical models are needed that mimic the complexity of a tumor. In this work, we established a novel three-dimensional (3D) model for patient-derived GBM cell lines. To analyze the volume and growth pattern of...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2023
Band / Volume:
15
Heft / Issue:
16
Volltext / DOI:
doi:10.3390/cancers15164051
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37627079
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Klinik und Poliklinik für Neurochirurgie (Prof. Meyer); Klinik und Poliklinik für RadioOnkologie und Strahlentherapie (Prof. Combs)
 BibTeX