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Titel:

EGFR and Cortactin: Markers for potential double target therapy in oral squamous cell carcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Bissinger, Oliver; Kolk, Andreas; Drecoll, Enken; Straub, Melanie; Lutz, Christina; Wolff, Klaus-Dietrich; Götz, Carolin
Abstract:
Survival periods of patients following surgical therapy of oral squamous cell carcinoma (OSCC) have previously been demonstrated to decrease over recent decades. Epidermal growth factor receptor (EGFR) and Cortactin are molecular markers that are important in tumour progression and development, and interact within the EGF pathway. Although EGFR antibody therapy exists, sufficient efforts for increased survival are still lacking due to the present limited response rates. The aim of the present st...     »
Zeitschriftentitel:
Exp Ther Med
Jahr:
2017
Band / Volume:
14
Heft / Issue:
5
Seitenangaben Beitrag:
4620-4626
Sprache:
eng
Volltext / DOI:
doi:10.3892/etm.2017.5120
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29201160
Print-ISSN:
1792-0981
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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