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Title:

A rare case of H3K27-altered diffuse midline glioma with multiple osseous and spinal metastases at the time of diagnosis.

Document type:
Case Reports; Journal Article
Author(s):
Aftahy, A Kaywan; Butenschoen, Vicki M; Hoenikl, Lisa; Liesche-Starnecker, Friederike; Wiestler, Benedikt; Schmidt-Graf, Friederike; Meyer, Bernhard; Gempt, Jens
Abstract:
BACKGROUND: H3K27-altered diffuse midline gliomas are uncommon central nervous system tumors with extremely poor prognoses. CASE PRESENTATION: We report the case of a 24-year-old man patient with multiple, inter alia osseous metastases who presented with back pain, hemi-hypoesthesia, and hemi-hyperhidrosis. The patient underwent combined radio-chemotherapy and demonstrated temporary improvement before deteriorating. CONCLUSIONS: H3K27-altered diffuse midline glioma presents an infrequent but cru...     »
Journal title abbreviation:
BMC Neurol
Year:
2023
Journal volume:
23
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s12883-023-03135-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36855102
Print-ISSN:
1471-2377
TUM Institution:
Klinik und Poliklinik für Neurochirurgie (Prof. Meyer); Klinik und Poliklinik für Neurologie (Prof. Hemmer); Professur für AI for Image-Guided Diagnosis and Therapy (Prof. Wiestler); Professur für Neuroradiologie (Prof. Zimmer)
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