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Titel:

CD133-enriched CD34(-) (CD33/CD38/CD71)(-) cord blood cells acquire CD34 prior to cell division and hematopoietic activity is exclusively associated with CD34 expression.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Götze, KS; Schiemann, M; Marz, S; Jacobs, VR; Debus, G; Peschel, C; Oostendorp, RA
Abstract:
We compared the cell division behavior of CD34(-) and CD34(+) (CD33/CD38/CD71)-negative (Lin(-)) CD133(+) cord blood cells stimulated with the cytokines Flt3-ligand, stem cell factor, and thrombopoietin. Within a 4-day time frame, Lin(-)CD34(-) CD133(+) (CD34(-)) cells underwent more cell divisions in serum-free culture than their Lin(-)CD34(+) CD133(+) (CD34(+)) counterparts. The majority of CD34(-) cells acquired expression of CD34 in vitro, including most undivided cells. Moreover, hematopoie...     »
Zeitschriftentitel:
Exp Hematol
Jahr:
2007
Band / Volume:
35
Heft / Issue:
9
Seitenangaben Beitrag:
1408-14
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.exphem.2007.05.016
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17656010
Print-ISSN:
0301-472X
TUM Einrichtung:
Frauenklinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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