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Titel:

Efficacy of neoadjuvant pertuzumab in addition to chemotherapy and trastuzumab in routine clinical treatment of patients with primary breast cancer: a multicentric analysis.

Dokumenttyp:
Journal Article
Autor(en):
Fasching, Peter A; Hartkopf, Andreas D; Gass, Paul; Häberle, Lothar; Akpolat-Basci, Leyla; Hein, Alexander; Volz, Bernhard; Taran, Florin-Andrei; Nabieva, Naiba; Pott, Birgit; Overkamp, Friedrich; Einarson, Hanna; Hadji, Peyman; Tesch, Hans; Ettl, Johannes; Lüftner, Diana; Wallwiener, Markus; Müller, Volkmar; Janni, Wolfgang; Fehm, Tanja N; Schneeweiss, Andreas; Untch, Michael; Pott, Dirk; Lux, Michael P; Geyer, Thomas; Liedtke, Cornelia; Seeger, Harald; Wetzig, Sarah; Hartmann, Arndt; Schulz-We...     »
Abstract:
PURPOSE: Neoadjuvant combination treatment with chemotherapy (CTX), trastuzumab (TZM), and pertuzumab (PTZ) has been shown to result in higher pathological complete response rates (pCR) in comparison with treatment with chemotherapy and trastuzumab (CTX/TZM). This analysis was aimed at real-world validation of these results from prospective randomized trials. METHODS: In a retrospective analysis conducted in the PRAEGNANT network, patients were eligible for inclusion if they had either received...     »
Zeitschriftentitel:
Breast Cancer Res Treat
Jahr:
2019
Band / Volume:
173
Heft / Issue:
2
Seitenangaben Beitrag:
319-328
Volltext / DOI:
doi:10.1007/s10549-018-5008-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30324275
Print-ISSN:
0167-6806
TUM Einrichtung:
Frauenklinik und Poliklinik
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