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Titel:

MCPIP-1 Restricts Inflammation via Promoting Apoptosis of Neutrophils.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Dobosz, Ewelina; Wadowska, Marta; Kaminska, Marta; Wilamowski, Mateusz; Honarpisheh, Mohsen; Bryzek, Danuta; Potempa, Jan; Jura, Jolanta; Lech, Maciej; Koziel, Joanna
Abstract:
Monocyte chemoattractant protein-induced protein-1 (MCPIP-1) is a potent inhibitor of inflammatory response to pathogens. Acting as endonuclease against transcripts of inflammatory cytokines or transcription factors MCPIP-1 can significantly reduce the cytokine storm, thus limiting the tissue damage. As the adequate resolution of inflammation depends also on the efficient clearance of accumulated neutrophils, we focused on the role of MCPIP-1 in apoptosis and retention of neutrophils. We used pe...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2021
Band / Volume:
12
Volltext / DOI:
doi:10.3389/fimmu.2021.627922
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33717148
Print-ISSN:
1664-3224
TUM Einrichtung:
602; Fachgebiet Nephrologie (Prof. Heemann)
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