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Titel:

Dclk1-expressing tuft cells: critical modulators of the intestinal niche?

Dokumenttyp:
Journal Article; Review; 4
Autor(en):
Middelhoff, Moritz; Westphalen, C Benedikt; Hayakawa, Yoku; Yan, Kelley S; Gershon, Michael D; Wang, Timothy C; Quante, Michael
Abstract:
-expressing tuft cells constitute a unique intestinal epithelial lineage that is distinct from enterocytes, Paneth cells, goblet cells, and enteroendocrine cells. Tuft cells express taste-related receptors and distinct transcription factors and interact closely with the enteric nervous system, suggesting a chemosensory cell lineage. In addition, recent work has shown that tuft cells interact closely with cells of the immune system, with a critical role in the cellular regulatory network governin...     »
Zeitschriftentitel:
Am J Physiol Gastrointest Liver Physiol
Jahr:
2017
Band / Volume:
313
Heft / Issue:
4
Seitenangaben Beitrag:
G285-G299
Sprache:
eng
Volltext / DOI:
doi:10.1152/ajpgi.00073.2017
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28684459
Print-ISSN:
0193-1857
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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