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Titel:

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB.

Dokumenttyp:
Journal Article; Review
Autor(en):
Kabacaoglu, Derya; Ruess, Dietrich A; Ai, Jiaoyu; Algül, Hana
Abstract:
Regulation of Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)/Rel transcription factors (TFs) is extremely cell-type-specific owing to their ability to act disparately in the context of cellular homeostasis driven by cellular fate and the microenvironment. This is also valid for tumor cells in which every single component shows heterogenic effects. Whereas many studies highlighted a per se oncogenic function for NF-κB/Rel TFs across cancers, recent advances in the field re...     »
Zeitschriftentitel:
Cancers
Jahr:
2019
Band / Volume:
11
Heft / Issue:
7
Volltext / DOI:
doi:10.3390/cancers11070937
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31277415
Print-ISSN:
2072-6694
TUM Einrichtung:
Lehrstuhl für Tumormetabolismus (Prof. Algül)
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