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Title:

Retinal ganglion cell loss is associated with future disability worsening in early relapsing-remitting multiple sclerosis.

Document type:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Wauschkuhn, Josephine; Solorza Buenrostro, Gilberto; Aly, Lilian; Asseyer, Susanna; Wicklein, Rebecca; Hartberger, Julia Maria; Ruprecht, Klemens; Mühlau, Mark; Schmitz-Hübsch, Tanja; Chien, Claudia; Berthele, Achim; Brandt, Alexander U; Korn, Thomas; Paul, Friedemann; Hemmer, Bernhard; Zimmermann, Hanna G; Knier, Benjamin
Abstract:
BACKGROUND AND PURPOSE: Thinning of the retinal combined ganglion cell and inner plexiform layer (GCIP) as measured by optical coherence tomography (OCT) is a common finding in patients with multiple sclerosis. This study aimed to investigate whether a single retinal OCT analysis allows prediction of future disease activity after a first demyelinating event. METHODS: This observational cohort study included 201 patients with recently diagnosed clinically isolated syndrome or relapsing-remitting...     »
Journal title abbreviation:
Eur J Neurol
Year:
2023
Journal volume:
30
Journal issue:
4
Pages contribution:
982-990
Fulltext / DOI:
doi:10.1111/ene.15681
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36635219
Print-ISSN:
1351-5101
TUM Institution:
Klinik und Poliklinik für Neurologie (Prof. Hemmer); Molekulare Immunologie (Prof. Knolle)
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