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Title:

Proliferation and apoptosis after whole-body irradiation: longitudinal PET study in a mouse model.

Document type:
Journal Article
Author(s):
Meindl, Maria; Bläske, Alexandra; Steiger, Katja; Lindner, Simon; Lindheimer, Felix; Lauber, Kirsten; Brix, Nikko; von Ungern-Sternberg, Barbara; Oos, Rosel; Palumbo, Giovanna; Böning, Guido; Schüle, Simone; Majewski, Matthäus; Port, Matthias; Ziegler, Sibylle; Bartenstein, Peter
Abstract:
PURPOSE: A reliable method for regional in vivo imaging of radiation-induced cellular damage would be of great importance for the detection of therapy-induced injury to healthy tissue and the choice of adequate treatment of radiation emergency patients in both civilian and military events. This study aimed to investigate in a mouse model if positron emission tomography (PET) imaging with proliferation and apoptosis markers is potentially suitable for this purpose. METHODS: Four groups, including...     »
Journal title abbreviation:
Eur J Nucl Med Mol Imaging
Year:
2024
Journal volume:
51
Journal issue:
2
Pages contribution:
395-404
Fulltext / DOI:
doi:10.1007/s00259-023-06430-x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37796306
Print-ISSN:
1619-7070
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)
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