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Title:

The Impact of PSMA PET-Based Eligibility Criteria Used in the Prospective Phase II TheraP Trial in Metastatic Castration-Resistant Prostate Cancer Patients Undergoing Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy.

Document type:
Journal Article
Author(s):
Karimzadeh, Amir; Heck, Matthias; Tauber, Robert; Solaris, Esteban; Nekolla, Stephan; Knorr, Karina; Haller, Bernhard; D'Alessandria, Calogero; Weber, Wolfgang A; Eiber, Matthias; Rauscher, Isabel
Abstract:
Prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) has shown encouraging results for treatment of metastatic castration-resistant prostate cancer (mCRPC) in the prospective, multicenter, randomized phase II TheraP study. The inclusion criteria for that study comprised a pretherapeutic 68Ga-PSMA-11 PET scan showing sufficient tumor uptake using a predefined threshold and the absence of 18F-FDG-positive, PSMA ligand-negative tumor lesions. However, the prognostic value of these PE...     »
Journal title abbreviation:
J Nucl Med
Year:
2023
Journal volume:
64
Journal issue:
8
Pages contribution:
1252-1258
Fulltext / DOI:
doi:10.2967/jnumed.122.265346
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37290796
Print-ISSN:
0161-5505
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin (Prof. Weber); Klinik und Poliklinik für Urologie (Prof. Gschwend); Lehrstuhl für Medizinische Informatik (Prof. Boeker)
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