Kremer, Veerle;Stanicek, Laura;van Ingen, Eva;Bink, Diewertje I;Hilderink, Sarah;Tijsen, Anke J;Wittig, Ilka;Mägdefessel, Lars;Nossent, Anne Yaël;Boon, Reinier A
The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing.
J Cell Sci
2022
135
12

Wang, Ying;Gao, Hua;Wang, Fudi;Ye, Zhongde;Mokry, Michal;Turner, Adam W;Ye, Jianqin;Koplev, Simon;Luo, Lingfeng;Alsaigh, Tom;Adkar, Shaunak S;Elishaev, Maria;Gao, Xiangyu;Maegdefessel, Lars;Björkegren, Johan L M;Pasterkamp, Gerard;Miller, Clint L;Ross, Elsie G;Leeper, Nicholas J
Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells.
Cardiovasc Res
2022
118
13
2792-2804

Jarr, Kai-Uwe;Ye, Jianqin;Kojima, Yoko;Ye, Zhongde;Gao, Hua;Schmid, Sofie;Luo, Lingfeng;Baylis, Richard A;Lotfi, Mozhgan;Lopez, Nicolas;Eberhard, Anne V;Smith, Bryan Ronain;Weissman, Irving L;Maegdefessel, Lars;Leeper, Nicholas J
The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis.
Nat Cardiovasc Res
2022
1
3
253-262

Edsfeldt, Andreas;Swart, Maarten;Singh, Pratibha;Dib, Lea;Sun, Jiangming;Cole, Jennifer E;Park, Inhye;Al-Sharify, Dania;Persson, Ana;Nitulescu, Mihaela;Borges, Patricia Das Neves;Kassiteridi, Christina;Goddard, Michael E;Lee, Regent;Volkov, Petr;Orho-Melander, Marju;Maegdefessel, Lars;Nilsson, Jan;Udalova, Irina;Goncalves, Isabel;Monaco, Claudia
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques.
Eur Heart J
2022
43
19
1864-1877

Hildebrand, Staffan;Ibrahim, Mohamed;Schlitzer, Andreas;Maegdefessel, Lars;Röll, Wilhelm;Pfeifer, Alexander
PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle.
Commun Biol
2022
5
1

Skenteris, Nikolaos T;Seime, Till;Witasp, Anna;Karlöf, Eva;Wasilewski, Grzegorz B;Heuschkel, Marina A;Jaminon, Armand M G;Oduor, Loureen;Dzhanaev, Robert;Kronqvist, Malin;Lengquist, Mariette;Peeters, Frederique E C M;Söderberg, Magnus;Hultgren, Rebecka;Roy, Joy;Maegdefessel, Lars;Arnardottir, Hildur;Bengtsson, Eva;Goncalves, Isabel;Quertermous, Thomas;Goettsch, Claudia;Stenvinkel, Peter;Schurgers, Leon J;Matic, Ljubica
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification.
Clin Transl Med
2022
12
2

Metschl, Susanne;Bruder, Lukas;Paloschi, Valentina;Jakob, Katharina;Reutersberg, Benedikt;Reeps, Christian;Maegdefessel, Lars;Gee, Michael;Eckstein, Hans-Henning;Pelisek, Jaroslav
Changes in Endocan and Dermatan Sulfate Are Associated with Biomechanical Properties of Abdominal Aortic Wall during Aneurysm Expansion and Rupture.
Thromb Haemost
2022
122
9
1513-1523

Zhou, Zhichao;Collado, Aida;Sun, Changyan;Tratsiakovich, Yahor;Mahdi, Ali;Winter, Hanna;Chernogubova, Ekaterina;Seime, Till;Narayanan, Sampath;Jiao, Tong;Jin, Hong;Alvarsson, Michael;Zheng, Xiaowei;Yang, Jiangning;Hedin, Ulf;Catrina, Sergiu-Bogdan;Maegdefessel, Lars;Pernow, John
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes.
Diabetes
2022
71
2
285-297

Oo, James A;Pálfi, Katalin;Warwick, Timothy;Wittig, Ilka;Prieto-Garcia, Cristian;Matkovic, Vigor;Tomašković, Ines;Boos, Frederike;Izquierdo Ponce, Judit;Teichmann, Tom;Petriukov, Kirill;Haydar, Shaza;Maegdefessel, Lars;Wu, Zhiyuan;Pham, Minh Duc;Krishnan, Jaya;Baker, Andrew H;Günther, Stefan;Ulrich, Helle D;Dikic, Ivan;Leisegang, Matthias S;Brandes, Ralf P
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.
Cell Rep
2022
41
7

Lim, Chrysania;Pratama, Muhammad Yogi;Rivera, Cristobal;Silvestro, Michele;Tsao, Philip S;Maegdefessel, Lars;Gallagher, Katherine A;Maldonado, Thomas;Ramkhelawon, Bhama
Linking single nucleotide polymorphisms to signaling blueprints in abdominal aortic aneurysms.
Sci Rep
2022
12
1