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Titel:

NF-κB in control of regulatory T cell development, identity, and function.

Dokumenttyp:
Journal Article; Review; Research Support, Non-U.S. Gov't
Autor(en):
Hövelmeyer, Nadine; Schmidt-Supprian, Marc; Ohnmacht, Caspar
Abstract:
Regulatory T cells (Treg cells) act as a major rheostat regulating the strength of immune responses, enabling tolerance of harmless foreign antigens, and preventing the development of pathogenic immune responses in various disease settings such as cancer and autoimmunity. Treg cells are present in all lymphoid and non-lymphoid tissues, and the latter often fulfill important tasks required for the physiology of their host organ. The activation of NF-κB transcription factors is a central pathway f...     »
Zeitschriftentitel:
J Mol Med
Jahr:
2022
Band / Volume:
100
Heft / Issue:
7
Seitenangaben Beitrag:
985-995
Volltext / DOI:
doi:10.1007/s00109-022-02215-1
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35672519
Print-ISSN:
0946-2716
TUM Einrichtung:
Experimentelle Hämatologie (Prof. Schmidt-Supprian); Lehrstuhl für Molekulare Allergologie und Umweltforschung (Prof. Schmidt-Weber)
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