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Titel:

Cortical Thin Patch Fraction Reflects Disease Burden in MS: The Mosaic Approach.

Dokumenttyp:
Journal Article
Autor(en):
Tahedl, Marlene; Wiltgen, Tun; Voon, Cui Ci; Berthele, Achim; Kirschke, Jan S; Hemmer, Bernhard; Mühlau, Mark; Zimmer, Claus; Wiestler, Benedikt
Abstract:
BACKGROUND AND PURPOSE: GM pathology plays an essential role in MS disability progression, emphasizing the importance of neuroradiologic biomarkers to capture the heterogeneity of cortical disease burden. This study aimed to assess the validity of a patch-wise, individual interpretation of cortical thickness data to identify GM pathology, the "mosaic approach," which was previously suggested as a biomarker for assessing and localizing atrophy. MATERIALS AND METHODS: We investigated the mosaic ap...     »
Zeitschriftentitel:
AJNR Am J Neuroradiol
Jahr:
2023
Band / Volume:
45
Heft / Issue:
1
Seitenangaben Beitrag:
82-89
Volltext / DOI:
doi:10.3174/ajnr.A8064
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/38164526
Print-ISSN:
0195-6108
TUM Einrichtung:
Klinik und Poliklinik für Neurologie (Prof. Hemmer); Professur für AI for Image-Guided Diagnosis and Therapy (Prof. Wiestler); Professur für Neuroradiologie (Prof. Zimmer)
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