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Titel:

Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration-the PINNACLE trial protocol.

Dokumenttyp:
Journal Article
Autor(en):
Sutton, Janice; Menten, Martin J; Riedl, Sophie; Bogunović, Hvroje; Leingang, Oliver; Anders, Philipp; Hagag, Ahmed M; Waldstein, Sebastian; Wilson, Amber; Cree, Angela J; Traber, Ghislaine; Fritsche, Lars G; Scholl, Hendrik; Rueckert, Daniel; Schmidt-Erfurth, Ursula; Sivaprasad, Sobha; Prevost, Toby; Lotery, Andrew
Abstract:
AIMS: Age-related macular degeneration (AMD) is characterised by a progressive loss of central vision. Intermediate AMD is a risk factor for progression to advanced stages categorised as geographic atrophy (GA) and neovascular AMD. However, rates of progression to advanced stages vary between individuals. Recent advances in imaging and computing technologies have enabled deep phenotyping of intermediate AMD. The aim of this project is to utilise machine learning (ML) and advanced statistical mod...     »
Zeitschriftentitel:
Eye
Jahr:
2023
Band / Volume:
37
Heft / Issue:
6
Seitenangaben Beitrag:
1275-1283
Volltext / DOI:
doi:10.1038/s41433-022-02097-0
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35614343
Print-ISSN:
0950-222X
TUM Einrichtung:
Institut für KI und Informatik in der Medizin (Prof. Rückert)
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