PURPOSE: It is shown that the steady state of rapid, TR-periodic steady-state free precession (SSFP) sequences at small to moderate flip angles exhibits a universal, approximate scaling law with respect to variations of B 1 + $$ {B}_1^{+} $$ . Implications for the accuracy and precision of relaxometry experiments are discussed. METHODS: The approximate scaling law is derived from and numerically tested against known analytical solutions. To assess the attainable estimator precision in a typical relaxometry experiment, we calculate the Cramér-Rao bound (CRB) and perform Monte Carlo (MC) simulations. RESULTS: The approximate universal scaling holds well up to moderate flip angles. For pure steady state relaxometry, we observe a significant precision penalty for simultaneous estimation of R 1 $$ {R}_1 $$ and B 1 + $$ {B}_1^{+} $$ , whereas good R 2 $$ {R}_2 $$ estimates can be obtained without even knowing the correct actual flip angle. CONCLUSION: Simultaneous estimation of R 1 $$ {R}_1 $$ and B 1 + $$ {B}_1^{+} $$ from a set of SSFP steady states alone is not advisable. Apart from separate B 1 + $$ {B}_1^{+} $$ measurements, the problem can be addressed by adding transient state information, but, depending on the situation, residual effects due to the scaling may still require some attention.      «

PURPOSE: It is shown that the steady state of rapid, TR-periodic steady-state free precession (SSFP) sequences at small to moderate flip angles exhibits a universal, approximate scaling law with respect to variations of B 1 + $$ {B}_1^{+} $$ . Implications for the accuracy and precision of relaxometry experiments are discussed. METHODS: The approximate scaling law is derived from and numerically tested against known analytical solutions. To assess the attainable estimator precision in a ty...     »