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Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression.
Cell Rep
2023
42
10

Andersen, Line Lykke;Huang, Yiqi;Urban, Christian;Oubraham, Lila;Winheim, Elena;Stafford, Che;Nagl, Dennis;O'Duill, Fionan;Ebert, Thomas;Engleitner, Thomas;Paludan, Søren Riis;Krug, Anne;Rad, Roland;Hornung, Veit;Pichlmair, Andreas
Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages.
EMBO J
2023
42
23

Frank, Daria;Patnana, Pradeep Kumar;Vorwerk, Jan;Mao, Lianghao;Gopal, Lavanya Mokada;Jung, Noelle;Hennig, Thorben;Ruhnke, Leo;Frenz, Joris Maximillian;Kuppusamy, Maithreyan;Autry, Robert;Wei, Lanying;Sun, Kaiyan;Mohammed Ahmed, Helal Mohammed;Künstner, Axel;Busch, Hauke;Müller, Heiko;Hutter, Stephan;Hoermann, Gregor;Liu, Longlong;Xie, Xiaoqing;Al-Matary, Yahya;Nimmagadda, Subbaiah Chary;Cano, Fiorella Charles;Heuser, Michael;Thol, Felicitas;Göhring, Gudrun;Steinemann, Doris;Thomale, Jürgen;Leitner, Theo;Fischer, Anja;Rad, Roland;Röllig, Christoph;Altmann, Heidi;Kunadt, Desiree;Berdel, Wolfgang E;Hüve, Jana;Neumann, Felix;Klingauf, Jürgen;Calderon, Virginie;Opalka, Bertram;Dührsen, Ulrich;Rosenbauer, Frank;Dugas, Martin;Varghese, Julian;Reinhardt, Hans Christian;von Bubnoff, Nikolas;Möröy, Tarik;Lenz, Georg;Batcha, Aarif M N;Giorgi, Marianna;Selvam, Murugan;Wang, Eunice;McWeeney, Shannon K;Tyner, Jeffrey W;Stölzel, Friedrich;Mann, Matthias;Jayavelu, Ashok Kumar;Khandanpour, Cyrus
Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.
Blood
2023
142
25
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Heidegger, Simon;Stritzke, Florian;Dahl, Sarah;Daßler-Plenker, Juliane;Joachim, Laura;Buschmann, Dominik;Fan, Kaiji;Sauer, Carolin M;Ludwig, Nils;Winter, Christof;Enssle, Stefan;Li, Suqi;Perl, Markus;Görgens, André;Haas, Tobias;Orberg, Erik Thiele;Göttert, Sascha;Wölfel, Catherine;Engleitner, Thomas;Cortés-Ciriano, Isidro;Rad, Roland;Herr, Wolfgang;Giebel, Bernd;Ruland, Jürgen;Bassermann, Florian;Coch, Christoph;Hartmann, Gunther;Poeck, Hendrik
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Cell Rep Med
2023
4
9

Su, Jinpeng;Brunner, Livia;Ates Oz, Edanur;Sacherl, Julia;Frank, Geraldine;Kerth, Helene Anne;Thiele, Frank;Wiegand, Marian;Mogler, Carolin;Aguilar, Julio Cesar;Knolle, Percy A;Collin, Nicolas;Kosinska, Anna D;Protzer, Ulrike
Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models.
J Hepatol
2023
78
4
717-730

Yahoo, Neda;Dudek, Michael;Knolle, Percy;Heikenwälder, Mathias
Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation.
J Hepatol
2023
79
2
538-551

Bergant, Valter;Schnepf, Daniel;de Andrade Krätzig, Niklas;Hubel, Philipp;Urban, Christian;Engleitner, Thomas;Dijkman, Ronald;Ryffel, Bernhard;Steiger, Katja;Knolle, Percy A;Kochs, Georg;Rad, Roland;Staeheli, Peter;Pichlmair, Andreas
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Nat Commun
2023
14
1

Hackstein, Carl-Philipp;Spitzer, Jasper;Symeonidis, Konstantinos;Horvatic, Helena;Bedke, Tanja;Steglich, Babett;Klein, Sabine;Assmus, Lisa M;Odainic, Alexandru;Szlapa, Jennifer;Kessler, Nina;Beyer, Marc;Schmithausen, Ricarda;Latz, Eicke;Flavell, Richard A;Garbi, Natalio;Kurts, Christian;Kümmerer, Beate M;Trebicka, Jonel;Roers, Axel;Huber, Samuel;Schmidt, Susanne V;Knolle, Percy A;Abdullah, Zeinab
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
J Hepatol
2023
79
1
150-166

Raab, René;Küderle, Arne;Zakreuskaya, Anastasiya;Stern, Ariel D;Klucken, Jochen;Kaissis, Georgios;Rueckert, Daniel;Boll, Susanne;Eils, Roland;Wagener, Harald;Eskofier, Bjoern M
Federated electronic health records for the European Health Data Space.
Lancet Digit. Health
2023
5
11
e840-e847

Greiwe, Gillis;Flick, Moritz;Hapfelmeier, Alexander;Winkler, Martin S;Nitzschke, Rainer;Frings, Daniel;Saugel, Bernd
Agreement between cardiac output measurements by pulse wave analysis using the Pressure Recording Analytical Method and transthoracic echocardiography in patients with veno-venous extracorporeal membrane oxygenation therapy: An observational method comparison.
Eur J Anaesthesiol
2023
40
6
436-441