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Titel:

Tumour cell budding and spread through air spaces in squamous cell carcinoma of the lung - Determination and validation of optimal prognostic cut-offs.

Dokumenttyp:
Journal Article
Autor(en):
Stögbauer, Fabian; Lautizi, Manuela; Kriegsmann, Mark; Winter, Hauke; Muley, Thomas; Kriegsmann, Katharina; Jesinghaus, Moritz; Baumbach, Jan; Schüffler, Peter; Weichert, Wilko; Kacprowski, Tim; Boxberg, Melanie
Abstract:
PURPOSE: Prognostic stratification of patients with squamous cell carcinomas of the lung (SCC-L) is challenging. Therefore, we investigated several histomorphological parameters (tumour cell budding (TCB), spread through air spaces (STAS), tumour-stroma-ratio, immune cell infiltration) which could potentially serve as prognostic parameters in SCC-L. We aimed to systematically determine optimal cut-off-values and assess the prognostic capability of these patterns. We furthermore assessed interobs...     »
Zeitschriftentitel:
Lung Cancer
Jahr:
2022
Band / Volume:
169
Seitenangaben Beitrag:
1-12
Volltext / DOI:
doi:10.1016/j.lungcan.2022.04.012
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35567921
Print-ISSN:
0169-5002
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Lehrstuhl für Translationale Tumorforschung (DKTK) (Prof. Saur)
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