CT-Guided Liver Biopsy: Evaluation of Spectral Data From Dual-Layer Detector CT for Improved Lesion Detection.

Sauter, Andreas P; Proksa, Roland; Knipfer, Andreas; Reischl, Stefan; Braren, Rickmer F; Nadjiri, Jonathan; Kopp, Felix; Noël, Peter B; Makowski, Markus R; Rummeny, Ernst J; Fingerle, Alexander A

doi:10.1007/s00270-023-03550-7

2023

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Title:: CT-Guided Liver Biopsy: Evaluation of Spectral Data From Dual-Layer Detector CT for Improved Lesion Detection.
Document type:: Journal Article
Author(s):: Sauter, Andreas P; Proksa, Roland; Knipfer, Andreas; Reischl, Stefan; Braren, Rickmer F; Nadjiri, Jonathan; Kopp, Felix; Noël, Peter B; Makowski, Markus R; Rummeny, Ernst J; Fingerle, Alexander A
Abstract:: PURPOSE: Evaluation of dual-layer spectral computed tomography (CT) for contrast enhancement during image-guided biopsy of liver lesions using virtual monoenergetic images (VMI) and virtual non-contrast (VNC) images. METHODS: Spectral CT data of 20 patients receiving CT-guided needle biopsy of focal liver lesions were used to generate VMI at energy levels from 40 to 200 keV and VNC images. Images were analyzed objectively regarding contrast-to-noise ratio between lesion center (CNRcent) or periphery (CNRperi) and normal liver parenchyma. Lesion visibility and image quality were evaluated on a 4-point Likert scale by two radiologists. RESULTS: Using VMI/VNC images, readers reported an increased visibility of the lesion compared to the conventional CT images in 18/20 cases. In 75% of cases, the highest visibility was derived by VMI-40. Showing all reconstructions simultaneously, VMI-40 offered the highest visibility in 75% of cases, followed by VNC in 12.5% of cases. Either CNRcent (17/20) or/and CNRperi (17/20) was higher (CNR increase > 50%) in 19/20 cases for VMI-40 or VNC images compared to conventional CT images. VMI-40 showed the highest CNRcent in 14 cases and the highest CNRperi in 12 cases. High image quality was present for all reconstructions with a minimum median of 3.5 for VMI-40 and VMI-50. CONCLUSIONS: When implemented in the CT scanner software, automated contrast enhancement of liver lesions during image-guided biopsy may facilitate the procedure. «
PURPOSE: Evaluation of dual-layer spectral computed tomography (CT) for contrast enhancement during image-guided biopsy of liver lesions using virtual monoenergetic images (VMI) and virtual non-contrast (VNC) images. METHODS: Spectral CT data of 20 patients receiving CT-guided needle biopsy of focal liver lesions were used to generate VMI at energy levels from 40 to 200 keV and VNC images. Images were analyzed objectively regarding contrast-to-noise ratio between lesion center (CNRcent) or perip... »
Journal title abbreviation:: Cardiovasc Intervent Radiol
Year:: 2023
Journal volume:: 46
Journal issue:: 11
Pages contribution:: 1621-1631
Fulltext / DOI:: doi:10.1007/s00270-023-03550-7
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/37759090
Print-ISSN:: 0174-1551
TUM Institution:: Institut für Diagnostische und Interventionelle Radiologie (Prof. Makowski); Professur für Interventionelle Radiologie (Prof. Paprottka)
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