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Titel:

Platelet mitochondrial membrane depolarization reflects disease severity in patients with preeclampsia.

Dokumenttyp:
Article; Journal Article
Autor(en):
Kraemer, Bjoern F; Hennis, Irina; Karge, Anne; Kraemer, Anne Katrin; Dreyer, Tobias F; Kiechle, Marion; Kuschel, Bettina; Bronger, Holger
Abstract:
BACKGROUND: Thrombocytopenia is a feared complication of preeclampsia (PE) that can additionally complicate the disease course and that carries a poor prognosis. The disease mechanisms of PE on a platelet level are poorly understood and only few platelet-based markers have been investigated. In sepsis, platelet mitochondrial membrane depolarization, a sensitive and early indicator of mitochondrial dysfunction and platelet cell death, correlates with disease severity and outcome as shown in previ...     »
Zeitschriftentitel:
Mol Med
Jahr:
2022
Band / Volume:
28
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s10020-022-00472-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35508969
Print-ISSN:
1076-1551
TUM Einrichtung:
Klinik und Poliklinik für Frauenheilkunde
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