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Title:

External Validity of Randomised Controlled Trials on Carotid Revascularisation: Trial Populations May Not Always Reflect Patients in Clinical Practice.

Document type:
Journal Article
Author(s):
Kallmayer, Michael A; Knappich, Christoph; Karlas, Angelos; Trenner, Matthias; Kuehnl, Andreas; Eckstein, Hans-Henning
Abstract:
OBJECTIVE: The external validity of randomised controlled trials (RCTs) and their transferability to clinical practice is under investigated. This study aimed to analyse the exclusion criteria of recent carotid RCTs comparing carotid endarterectomy (CEA) and carotid artery stenting, and to assess the eligibility of consecutive clinical practice cohorts to those RCTs. METHODS: An analysis of the clinical and anatomical exclusion criteria of RCTs for asymptomatic (SPACE-2, ACST-2, CREST-1, and CRE...     »
Journal title abbreviation:
Eur J Vasc Endovasc Surg
Year:
2022
Journal volume:
64
Journal issue:
5
Pages contribution:
452-460
Fulltext / DOI:
doi:10.1016/j.ejvs.2022.07.044
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35987505
Print-ISSN:
1078-5884
TUM Institution:
Professur für Gefäßchirurgie (Prof. Eckstein)
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