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Titel:

External Validity of Randomised Controlled Trials on Carotid Revascularisation: Trial Populations May Not Always Reflect Patients in Clinical Practice.

Dokumenttyp:
Journal Article
Autor(en):
Kallmayer, Michael A; Knappich, Christoph; Karlas, Angelos; Trenner, Matthias; Kuehnl, Andreas; Eckstein, Hans-Henning
Abstract:
OBJECTIVE: The external validity of randomised controlled trials (RCTs) and their transferability to clinical practice is under investigated. This study aimed to analyse the exclusion criteria of recent carotid RCTs comparing carotid endarterectomy (CEA) and carotid artery stenting, and to assess the eligibility of consecutive clinical practice cohorts to those RCTs. METHODS: An analysis of the clinical and anatomical exclusion criteria of RCTs for asymptomatic (SPACE-2, ACST-2, CREST-1, and CRE...     »
Zeitschriftentitel:
Eur J Vasc Endovasc Surg
Jahr:
2022
Band / Volume:
64
Heft / Issue:
5
Seitenangaben Beitrag:
452-460
Volltext / DOI:
doi:10.1016/j.ejvs.2022.07.044
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35987505
Print-ISSN:
1078-5884
TUM Einrichtung:
Professur für Gefäßchirurgie (Prof. Eckstein)
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