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Title:

CXCR4 peptide-based fluorescence endoscopy in a mouse model of Barrett's esophagus.

Document type:
Zeitschriftenaufsatz
Author(s):
Marcazzan, Sabrina; Braz Carvalho, Marcos J; Konrad, Matthias; Strangmann, Julia; Tenditnaya, Anna; Baumeister, Theresa; Schmid, Roland M; Wester, Hans-Jürgen; Ntziachristos, Vasilis; Gorpas, Dimitris; Wang, Timothy C; Schottelius, Margret; Quante, Michael
Abstract:
BACKGROUND: Near-infrared (NIR) fluorescence imaging has been emerging as a promising strategy to overcome the high number of early esophageal adenocarcinomas missed by white light endoscopy and random biopsy collection. We performed a preclinical assessment of fluorescence imaging and endoscopy using a novel CXCR4-targeted fluorescent peptide ligand in the L2-IL1B mouse model of Barrett's esophagus. METHODS: Six L2-IL1B mice with advanced stage of disease (12-16 months old) were injected with...     »
Journal title:
EJNMMI Research
Journal title abbreviation:
EJNMMI Res
Year:
2022
Journal volume:
12
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s13550-021-00875-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35006394
WWW:
https://ejnmmires.springeropen.com/articles/10.1186/s13550-021-00875-7
Print-ISSN:
2191-219X
TUM Institution:
Klinik und Poliklinik für Innere Medizin II, Gastroenterologie; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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