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Titel:

Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Hilvo, Mika; Meikle, Peter J; Pedersen, Eva Ringdal; Tell, Grethe S; Dhar, Indu; Brenner, Hermann; Schöttker, Ben; Lääperi, Mitja; Kauhanen, Dimple; Koistinen, Kaisa M; Jylhä, Antti; Huynh, Kevin; Mellett, Natalie A; Tonkin, Andrew M; Sullivan, David R; Simes, John; Nestel, Paul; Koenig, Wolfgang; Rothenbacher, Dietrich; Nygård, Ottar; Laaksonen, Reijo
Abstract:
AIMS: Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially cardiovascular death. As phospholipids have also been linked with CVD risk, we investigated whether the combination of ceramides with phosphatidylcholines (PCs) would be synergistic in the prediction of CVD events in patients with atherosclerotic coronary heart disease in three independent cohort studies. METHODS AND RESULTS: Ceramides and PCs were analysed using liquid chromato...     »
Zeitschriftentitel:
Eur Heart J
Jahr:
2020
Band / Volume:
41
Heft / Issue:
3
Seitenangaben Beitrag:
371-380
Volltext / DOI:
doi:10.1093/eurheartj/ehz387
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31209498
Print-ISSN:
0195-668X
TUM Einrichtung:
273; Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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