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Titel:

Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions.

Dokumenttyp:
Journal Article
Autor(en):
Steiger, Katja; Gross, Nina; Widholz, Sebastian A; Rad, Roland; Weichert, Wilko; Mogler, Carolin
Abstract:
Genetically engineered mouse models (GEMM) are an elegant tool to study liver carcinogenesis in vivo. Newly designed mouse models need detailed (histopathological) phenotyping when described for the first time to avoid misinterpretation and misconclusions. Many chemically induced models for hepatocarcinogenesis comprise a huge variety of histologically benign and malignant neoplastic, as well as non-neoplastic, lesions. Such comprehensive categorization data for GEMM are still missing. In this s...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2020
Band / Volume:
12
Heft / Issue:
8
Volltext / DOI:
doi:10.3390/cancers12082265
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32823526
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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