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Title:

Obesity, Diabetes, Coffee, Tea, and Cannabis Use Alter Risk for Alcohol-Related Cirrhosis in 2 Large Cohorts of High-Risk Drinkers.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Whitfield, John B; Masson, Steven; Liangpunsakul, Suthat; Mueller, Sebastian; Aithal, Guruprasad P; Eyer, Florian; Gleeson, Dermot; Thompson, Andrew; Stickel, Felix; Soyka, Michael; Muellhaupt, Beat; Daly, Ann K; Cordell, Heather J; Foroud, Tatiana; Lumeng, Lawrence; Pirmohamed, Munir; Nalpas, Bertrand; Jacquet, Jean-Marc; Moirand, Romain; Nahon, Pierre; Naveau, Sylvie; Perney, Pascal; Haber, Paul S; Seitz, Helmut K; Day, Christopher P; Mathurin, Philippe; Morgan, Timothy R; Seth, Devanshi
Abstract:
INTRODUCTION: Sustained high alcohol intake is necessary but not sufficient to produce alcohol-related cirrhosis. Identification of risk factors, apart from lifetime alcohol exposure, would assist in discovery of mechanisms and prediction of risk. METHODS: We conducted a multicenter case-control study (GenomALC) comparing 1,293 cases (with alcohol-related cirrhosis, 75.6% male) and 754 controls (with equivalent alcohol exposure but no evidence of liver disease, 73.6% male). Information confirmin...     »
Journal title abbreviation:
Am J Gastroenterol
Year:
2021
Journal volume:
116
Journal issue:
1
Pages contribution:
106-115
Fulltext / DOI:
doi:10.14309/ajg.0000000000000833
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32868629
Print-ISSN:
0002-9270
TUM Institution:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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