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Titel:

[Pathogenesis of acute pancreatitis].

Dokumenttyp:
Journal Article; Review
Autor(en):
Sendler, Matthias; Algül, Hana
Abstract:
Acute pancreatitis is characterized by the autodigestion of the pancreas by its own digestive enzymes. The pathophysiological onset of the disease occurs in the acinar cells. The normally inactive precursors of secreted proteases are prematurely activated and as a result digest the cells from within. The activation of trypsinogen to trypsin represents the key event as active trypsin activates further digestive enzymes and can therefore initiate the activation of the complete protease cascade. Th...     »
Zeitschriftentitel:
Internist (Berl)
Jahr:
2021
Band / Volume:
62
Heft / Issue:
10
Seitenangaben Beitrag:
1034-1043
Volltext / DOI:
doi:10.1007/s00108-021-01158-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34529120
Print-ISSN:
0020-9554
TUM Einrichtung:
Lehrstuhl für Tumormetabolismus (Prof. Algül)
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