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Titel:

Maternal vitamin B12 in mice positively regulates bone, but not muscle mass and strength in post-weaning and mature offspring

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Singh, Parminder; Telnova, Svetalana; Zhou, Bin; Mohamed, Abdalla D.; Mello, Vanessa De; Wackerhage, Henning; Guo, X. Edward; Panda, Amulya K.; Yadav, Vijay K.
Abstract:
Vitamin B12 deficiency has been shown to affect bone mass in rodents and negatively impact bone formation in humans. In this study using mouse models, we define the effect of B12 supplementation in the wild-type mother and B12 deficiency in a mouse genetic model (Gif−/− mice) during gestation on bone and muscle architecture and mechanical properties in the offspring. Analysis of bones from 4-wk-old offspring of the wild-type mother following vehicle or B12 supplementation during gestation (from...     »
Dewey Dezimalklassifikation:
610 Medizin und Gesundheit
Zeitschriftentitel:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Jahr:
2021
Band / Volume:
320
Jahr / Monat:
2021-06
Quartal:
2. Quartal
Monat:
Jun
Heft / Issue:
6
Seitenangaben Beitrag:
R984-R993
Nachgewiesen in:
Web of Science
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1152/ajpregu.00355.2020
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33759575
Verlag / Institution:
American Physiological Society
E-ISSN:
0363-61191522-1490
Impact Factor:
2,992
Scimago-Quartil:
Q2
Hinweise:
SCImago Journal &  Country Rank
Status:
Erstveröffentlichung
Publikationsdatum:
01.06.2021
Semester:
SS 21
TUM Einrichtung:
Sportbiologie
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