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Title:

Epigenetic modulators combination with chemotherapy in breast cancer cells.

Document type:
Article; Journal Article
Author(s):
Ari, Ferda; Napieralski, Rudolf; Akgun, Oguzhan; Magdolen, Viktor; Ulukaya, Engin
Abstract:
Despite the concerning adverse effects on tumour development, epigenetic drugs are very promising in cancer treatment. The aim of this study was to compare the differential effects of standard chemotherapy regimens (FEC: 5-fluorouracil plus epirubicine plus cyclophosphamide) in combination with epigenetic modulators (decitabine, valproic acid): (a) on gene methylation levels of selected tumour biomarkers (LINE-1, uPA, PAI-1, DAPK); (b) their expression status (uPA and PAI-1); (c) differentiati...     »
Journal title abbreviation:
Cell Biochem Funct
Year:
2021
Journal volume:
39
Journal issue:
4
Pages contribution:
571-583
Fulltext / DOI:
doi:10.1002/cbf.3626
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33608886
Print-ISSN:
0263-6484
TUM Institution:
Frauenklinik und Poliklinik
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