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Titel:

Epigenetic modulators combination with chemotherapy in breast cancer cells.

Dokumenttyp:
Article; Journal Article
Autor(en):
Ari, Ferda; Napieralski, Rudolf; Akgun, Oguzhan; Magdolen, Viktor; Ulukaya, Engin
Abstract:
Despite the concerning adverse effects on tumour development, epigenetic drugs are very promising in cancer treatment. The aim of this study was to compare the differential effects of standard chemotherapy regimens (FEC: 5-fluorouracil plus epirubicine plus cyclophosphamide) in combination with epigenetic modulators (decitabine, valproic acid): (a) on gene methylation levels of selected tumour biomarkers (LINE-1, uPA, PAI-1, DAPK); (b) their expression status (uPA and PAI-1); (c) differentiati...     »
Zeitschriftentitel:
Cell Biochem Funct
Jahr:
2021
Band / Volume:
39
Heft / Issue:
4
Seitenangaben Beitrag:
571-583
Volltext / DOI:
doi:10.1002/cbf.3626
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33608886
Print-ISSN:
0263-6484
TUM Einrichtung:
Frauenklinik und Poliklinik
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